Vaccine Research and Development

Vaccine Research and Development

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Table of Content: Volume 3, Issue 2

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Research Letter Pages 18-23

Thermo-Stability of Heat-Labile Contagious Bovine Pleuro- Neumonia Vaccine in Different Stabilisers

Authors: Sangdjinan Ndjetel, Oladosu Gbolahanmi, Gelagay Ayelet, Nwankpa Nick, Belay Hassen and Bodjo Charles

Abstract: All available vaccines for Contagious Bovine Pleuropneumonia (CBPP), a notifiable, highly contagious and fatal respiratory disease of cattle caused by Mycoplasma mycoides subsp. mycoides (Mmm), are heat-labile and still reliant on cold-chain technologies to ensure stability. With the associated significant production losses, prevalent antimicrobial resistance and substantial impact on livestock- dependent people, there is the need for effective control via vaccination. Protecting the live-attenuated, heat-labile CBPP vaccines against inactivation under elevated temperature especially in tropical Africa becomes pertinent.

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Research Letter Pages 16-17

Antibody Response at 1, 4, and 6 Month after a Third Dose of Intradermal Vaccination of PFE-BNT in Adults Who Have Completed Two-Doses of Sinovac (Inactivated Vaccine)

Authors: Wachiraporn Arunothong

Abstract: Studies reported waning of antibody level in people who have completed two doses of inactivated vaccine as time passes. WHO with support of the Strategic Advisory Group of Experts (SAGE) on Immunization and its COVID-19 Vaccines Working Group has announced the recommendation guidance for booster doses vaccination.

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